Positions available



           Welcome to the Liu Lab

We are recruiting talented postdoctoral fellows to develop targeted cancer therapeutics based on novel human single chain antibodies that bind to internalizing cell surface antigens overexpressed in cancer. The research includes novel human monoclonal antibody discovery by developing and screening phage and yeast antibody display libraries, antibody characterization with regard to internalization pathways and effects on cell signaling/growth/death, and development of antibody-drug conjugates (ADCs) and antibody-siRNA/miRNA delivery vehicles for therapeutic applications. Candidates should have a track record of proficiency in molecular biology including mutagenesis and molecular diversity library construction, cell biology including internalization and signaling pathway analysis, protein chemistry including immunoprecipitation and protein/antibody production in bacteria and mammalian hosts, or conjugation chemistry with a particular emphasis on antibody conjugation with small molecule drugs or oligonucleotides. Interested individuals should submit (1) a curriculum vitae, (2) contact information of three references, and (3) a brief research plan to Prof. Bin Liu at recruit@liulab.ucsf.edu