Antibody Cancer Therapeutics

           Welcome to the Liu Lab

What we do

Our research group is focusing on developing novel human monoclonal antibody-based targeted cancer therapeutics. Our strategy is to develop and utilize an antibody library selection approach to functionally probe the internalizing cell surface epitope space associated with living tumor cells residing in their tissue microenvironment, and identify novel antibody-antigen/epitope interactions that can be exploited for therapeutic targeting. For translation, we are focusing on developing antibody drug conjugates (ADCs) and targeted siRNA/miRNA delivery based on novel internalizing antibodies discovered in the lab for cancer treatment.