Liu Lab - UCSF

The John Liu Laboratory at UCSF is an interdisciplinary basic and translational research group dedicated to the advancement of knowledge to improve the diagnosis and treatment of brain tumors. We develop and apply cutting-edge functional genomic and bioengineering approaches collaboratively to achieve this mission.

We are recruiting a Postdoctoral Scholar to develop and evaluate novel brain tumor therapeutics. Contact [email protected] for additional information.

News

6/5/26
Preprint
DNA-PKcs inhibition sensitizes glioblastoma to radiotherapy through reprogramming of tumor cell states and immune microenvironment cell types is out in preprint.
6/1/26
People
Jiachen Shi joins the lab as a Postdoctoral Scholar from the University of Virginia. Teerithveen Pasricha joins the lab as a Bioengineering PhD student. Welcome!
5/1/26
Grant
The Liu Lab is awarded grants from The Lower Grade Glioma Research Collective to develop CRISPR-based therapeutics for IDH mutant brain tumors, as well as the NIH/NCI to investigate ways to improve the efficacy of radiation therapy for glioblastoma.
4/1/26
Award
Congratulations to Sasha Sengelmann for receiving a Rose Hills Scholarship, Violet Hering for receiving a UC Berkeley Summer Undergraduate Research Fellowship, and Krish Raval for receiving a Caltech Summer Undergraduate Research Fellowship to support their thesis research in the lab!
2/1/26
Preprint
Collaborative preprint out with James Nuñez's lab at UC Berkeley on LEMONmethyl-seq: Targeted long-read DNA methylation profiling.
12/18/25
Award
The Liu Lab is one of three recipients of the 2025 Sontag Foundation Distinguished Scientist Award! Read the news article →
11/23/25
People
Akane, I-Ching, Shirley, and John deliver presentations at the 2025 Society for Neuro-Oncology Annual Meeting in Honolulu, Hawaii.
8/20/25
Grant
The Liu Lab is awarded grants from the V Foundation and the Weill Neurohub Investigator Program!
6/16/25
People
Christopher Zou departs the lab for the Stanford Genetics PhD program and an internship at FutureHouse. Francis Chalissery joins as a Volunteer AI Computational Scientist from Retool.
2/25/25
Paper
CRISPRoff epigenome editing in glioma manuscript is out in Neuro-Oncology!
2/14/25
People
Violet Hering and Krish Raval join the lab as undergraduate researchers from UC Berkeley.
12/23/24
People
Zerong Ma joins the lab as a Postdoctoral Scholar from the University of New South Wales and Childrens' Cancer Institute.
10/21/24
People
Akane Hubbard joins the lab as a Staff Research Associate from University of Michigan and Caribou Biosciences.
10/7/24
Paper
In vivo perturb-seq in intact brain tumors manuscript is out in Genome Biology!
9/3/24
People
I-Ching Wang joins the lab from Baylor College of Medicine as a postdoc.